The MedChem Lab Milestones
- Dr Roberta Listro wins the ACS prize for the best poster Elements for Future, SCI 2024
- Martina Garbagnoli and Roberta Listro win best Oral and Poster awards at P. Ehrlich MedChem 2024
- Federica Piaggi wins “Ing. Giacomo Bonaiuti” prize by Bracco Foundation
- Patent selected to participate to the Meet in Italy for Life Sciences brokerage event
- Dr Sara Salvi wins Premio di Laurea Oreste Pessina 2024
Latest Congress and dissemination
- Dr Roberta Listro wins the ACS prize for the best poster Elements for Future, SCI 2024
- 4th MMCS: Harnessing the Power of New Drug Modalities Part of the Molecules Medicinal Chemistry Symposium series
- 52°Congresso nazionale della società italiana di microbiologia, SIM 2024
- EFMC-ACSMEDI Medicinal Chemistry Frontiers 2024, Utrecht, Netherland
- Martina Garbagnoli and Roberta Listro win best Oral and Poster awards at P. Ehrlich MedChem 2024
- NBFC Events 2024
Publications
- New LsrK ligands as AI-2 Quorum Sensing Interfering Compounds Against Biofilm FormationMilli G., Pellegrini A., Listro R., Fasolini M., Pagano K., Ragona L., Pietrocola G., Linciano P., Collina S. (2024) Journal of Medicinal Chemistry DOI: 10.1021/acs.jmedchem.4c01266 ABSTRACT: Antimicrobial resistance (AMR) represents a critical global health crisis. An innovative strategy to deal with AMR is to interfere with biofilm formation and bacterial quorum sensing (QS). In this study,
- Biophysical Assays for Investigating Modulators of Macromolecular Complexes: An OverviewContinuous-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant CompoundsGarbagnoli M., Linciano P., Listro R., Rossino G., Vasile F., Collina S. (2024) ACS Omega 9(16), 17691–17705 DOI: 10.1021/acsomega.4c01309 ABSTRACT: Drug discovery is a lengthy and intricate process, and in its early stage, crucial steps are the selection of the therapeutic target and the identification of novel ligands. Most targets are dysregulated in pathogenic cells; typically, their
- A Green Heck Reaction Protocol towards Trisubstituted Alkenes, Versatile Pharmaceutical Intermediates.Rossino G., Marrubini G., Brindisi M., Granje M., Linciano P., Rossi D., Collina, S. (2024) Front. Chem. 12, 1431382 DOI: 10.3389/fchem.2024.1431382 ABSTRACT: The Heck reaction is widely employed to build a variety of biologically relevant scaffolds and has been successfully implemented in the production of active pharmaceutical ingredients (APIs). Typically, the reaction with terminal alkenes gives
- Effects of Growing Areas, Pruning Wound Protection Products, and Phenological Stage on the Stilbene Composition of Grapevine (Vitis vinifera L.) CanesIngrà C., Del Frari G., Favole M., Tumminelli E., Rossi D., Collina S., Prati M., Boavida Ferreira R., Ferrandino A. (2024) Journal of Agricultural and Food Chemistry, 72(20) 11465–11479 DOI: 10.1021/acs.jafc.4c00583 ABSTRACT: Applying plant protection products (PPP) on grapevine pruning wounds is a viticultural practice used to mitigate the spread of grapevine tuck disease, which is
- Neurodegeneration: can metabolites from Eremurus persicus help?Cavalloro V., Marchesi N., Linciano P., Rossi D., Irene L., Campagnoli M., Fossati A., Ahmed K.M., Malacrida A., Miloso M., Mazzeo G., Abbate S., Longhi G., Ambrosio F.A., Costa G., Alcaro S., Pascale A., Martino E., Collina S. (2024) Front. Pharmacol. 15, 1309766 DOI: 10.3389/fphar.2024.1309766 ABSTRACT: The number of patients affected by neurodegenerative diseases is increasing