{"id":398,"date":"2020-07-27T16:50:51","date_gmt":"2020-07-27T14:50:51","guid":{"rendered":"https:\/\/labmedchem.unipv.it\/?page_id=398"},"modified":"2025-07-04T10:09:10","modified_gmt":"2025-07-04T08:09:10","slug":"publications","status":"publish","type":"page","link":"https:\/\/labmedchem.unipv.it\/index.php\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n

Cavalloro, V.;\u00a0Malacrida, A.; Miloso, M.;\u00a0Ronchi, D.;\u00a0Porta, A.; Fossati, A.;\u00a0Gheza, G.;\u00a0De Siervi, S.;\u00a0Mantovani, S.;\u00a0Oliviero, B.;\u00a0Mondelli, M.U.;\u00a0Pugliese, L.;\u00a0Turato, C.;\u00a0Martino, E.;\u00a0Collina, S.
From lichen to organoids: Usnic acid enantiomers show promise against Cholangiocarcinoma via MNK2 targeting and MAPK pathway modulation<\/strong>
(2025) Biomedicine and Pharmacotherapy<\/em>, 188 118208
DOI: 10.1016\/j.biopha.2025.118208<\/a><\/p>\n\n\n\n

Tumminelli, E.; Cavalloro, V.; Ingr\u00e0, C.; Ferrandino, A.; Porta, A.; Marrubini, G.; Martino, E., Rossi D.; Collina, S.
Vineyard pruning-wood waste valorisation: sustainable extraction of bioactive compounds<\/strong>
(2025) Front. Chem<\/em>., 13 1597833
DOI: 10.3389\/fchem.2025.1597833<\/a><\/p>\n\n\n\n

Cavalloro, V.; Robustelli della Cuna, F.S.; Malovini, A.; Villa, C.; Sottani, C.; Balestra, M.; Bracco, F.; Martino, E.; Collina, S.
Essential Oils from\u00a0Papaver rho<\/em><\/strong>e<\/em>as<\/em>\u00a0and Their Metabolomic<\/strong> Profiling<\/strong>.
(2024) Metabolites<\/em>,\u00a014, 664
DOI: 10.3390\/metabo14120664<\/a><\/p>\n\n\n\n

Listro, R.; Rossino, G.; Cavalloro, V.; Rossi, D.; Boiocchi, M.; Robescu, M.S.; Bavaro, T.; Franchini, S.; Sorbi, C.; De Amici, M.; Linciano, P.; Collina, S.
1,3-Dithiolane as a Privileged Scaffold in Bioactive Derivatives: Chiral Resolution and Assignment of Absolute Configuration.\u00a0<\/strong>
(2024) Int. J. Mol. Sci.<\/em>,\u00a025, 12880
DOI: 10.3390\/ijms252312880<\/a><\/p>\n\n\n\n

Gado, I.; Garbagnoli, M.; Ambrosio, F.A.; Listro, R.; Parafioriti, M.; Cauteruccio, S.; Rossi, D.; Linciano, P.; Costa, G.; Alcaro, S.; Vasile, F.; Collina,S.
Peptide Nucleic Acids in Saturation Transfer Difference Nuclear Magnetic Resonance Experiments: A Simple and Valuable Tool for Studying HuR\u2013Small Molecule Complexes<\/strong>
(2024) ACS Omega<\/em>, 9(45) 45147\u201345158
DOI: 10.1021\/acsomega.4c06244<\/a><\/p>\n\n\n\n

Milli, G.; Pellegrini, A.; Listro, R.; Fasolini, M.; Pagano, K.; Ragona, L.; Pietrocola, G.; Linciano, P.; Collina, S.
New LsrK ligands as AI-2 Quorum Sensing Interfering Compounds Against Biofilm Formation<\/strong>
(2024)\u00a0Journal of Medicinal Chemistry<\/em>, ASAP
DOI: 10.1021\/acs.jmedchem.4c01266<\/a><\/p>\n\n\n\n

Ingr\u00e0 C., Del Frari G., Favole M., Tumminelli E., Rossi D., Collina S., Prati M., Boavida Ferreira R., Ferrandino A.
Effects of Growing Areas, Pruning Wound Protection Products, and Phenological Stage on the Stilbene Composition of Grapevine (Vitis vinifera<\/em> L.) Canes<\/strong>
(2024) Journal of Agricultural and Food Chemistry<\/em>, 72(20) 11465\u201311479
DOI: 10.1021\/acs.jafc.4c00583<\/a><\/p>\n\n\n\n

Garbagnoli M., Linciano P., Listro R., Rossino G., Vasile F., Collina S.
Biophysical Assays for Investigating Modulators of Macromolecular Complexes: An Overview<\/strong>
(2024) ACS Omega,<\/em> 9(16), 17691\u201317705
DOI: 10.1021\/acsomega.4c01309<\/a><\/p>\n\n\n\n

Cavalloro, V.; Pagliari, S.; Gosetti, F.; Campone, L.; Sottani, C.; Collina, S.; Martino, E.; Robustelli della Cuna, F.S.
Qualitative Metabolite Profiling of Orchis purpurea<\/em> Huds. by GC and UHPLC\/MS Approaches<\/strong>
(2024) Plants,<\/em> 13<\/em>, 1064
DOI: 10.3390\/plants13081064<\/a><\/p>\n\n\n\n

Trapp, O.; Berova, N.; Collina, S.; Pescitelli, G.
Chiral separations: Recent developments in chiral stationary phases and chromatographic separations of chiral compounds<\/strong>
(2024) Chirality,<\/em> 36(3), e23657
DOI: 10.1002\/chir.23657<\/a><\/p>\n\n\n\n

Rossino, G.; Marrubini, G.; Brindisi, M.; Granje, M.; Linciano, P.; Rossi, D.; Collina, S.
A green Heck reaction protocol towards trisubstituted alkenes, versatile pharmaceutical intermediates<\/strong>
(2024) Front. Chem.,<\/em> 12, 1431382
DOI: 10.3389\/fchem.2024.1431382<\/a><\/p>\n\n\n\n

Listro, R.; Marra, A.; Cavalloro, V.; Rossino, G.; Linciano, P.; Rossi, D.; Casali, E.; De Amici, M.; Mazzeo, G.; Longhi, G.; Fus\u00e8, M.; Dondio, G., Pellavio, G.; Laforenza, U.; Schepmann, D.; W\u00fcnsch, B.; Collina, S.
Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers<\/strong>
(2024) Journal of Pharmaceutical and Biomedical Analysis, 239<\/em>, 115902<\/em>
DOI: 10.1016\/j.jpba.2023.115902<\/a><\/p>\n\n\n\n

Cavalloro, V.; Marchesi, N.; Linciano, P.; Rossi, D.; Campagnoli, L.I.M.; Fossati, A.; Ahmed, K.M.; Malacrida, A.; Miloso, M.; Mazzeo, G.; Abbate, S.; Longhi, G.; Ambrosio, F.A.; Costa, G.; Alcaro, S.; Pascale, A.; Martino, E.; Collina, S.
Neurodegeneration: can metabolites from Eremurus persicus help?<\/strong>
(2024) Front. Pharmacol, 15<\/em>, 1309766<\/em>
DOI: 10.3389\/fphar.2024.1309766<\/a><\/p>\n\n\n\n

Linciano, P.; Pozzi, C.; Tassone, G.; Landi, G.; Mangani, S.; Santucci, M.; Luciani, R.; Ferrari, S.; Santarem, N.; Tagliazucchi, L.; Cordeiro-da-Silva, A.; Tonelli, M.; Tondi, D.; Bertarini, L.; Gul, S.; Witt, G.; Moraes, C.B.; Costantino, L.; Costi, M.P.
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents<\/strong>
(2024) European Journal of Medicinal Chemistry,<\/em> 264, 115946
DOI: 10.1016\/j.ejmech.2023.115946<\/a><\/p>\n\n\n\n

Pescitelli, G.; Di Bari, L.; Lacour, J.; Oda, R.; Berova, N.; Trapp, O.; Collina, S.
Chiral materials: Recent progress in structural analysis and emerging new technologies<\/strong>
(2023) Chirality, Editorial<\/em>
DOI: 10.1002\/chir.23609<\/a><\/p>\n\n\n\n

Cavalloro, V.; Marrubini G.; Rossino, G.; Martino, E.; Collina, S.
Combining DoE and MASE: a winning strategy for the isolation of natural bioactive compounds from plant materials<\/strong>
(2023) Green Chemistry, 26, 244-258 <\/em>
DOI: 10.1039\/D3GC03952H<\/a><\/p>\n\n\n\n

Linciano, P.; Quotadamo, A.; Luciani, R.; Santucci, M.; Zorn, K.M.; Foil, D.H.; Lane, T.R.; Cordeiro da Silva, A.; Santarem, N., B; Moraes, C.; Freitas-Junior, L.; Wittig, U.; Mueller, W.; Tonelli, M.; Ferrari, S.; Venturelli, A.; Gul, S.; Kuzikov, M.; Ellinger, B.; Reinshagen, J.; Ekins, S.; Costi, M.P.
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents<\/strong>
(2023) Journal of Medicinal Chemistry<\/em>, 66(22), 15230-15255
DOI: 10.1021\/acs.jmedchem.3c01322<\/a><\/p>\n\n\n\n

Della Volpe, S.; Listro, R.; Ambrosio, F.A.; Garbagnoli, M.; Linciano, P.; Rossi, D.; Costa, G.; Alcaro, S.; Vasile, F.; Hirsch, A.K.K.; Collina, S.
Identification of HuR\u2013RNA Interfering Compounds by Dynamic Combinatorial Chemistry and Fluorescence Polarization<\/strong>
(2023) ACS Med. Chem. Lett., 14(11), 1509\u20131516<\/em>
DOI: 10.1021\/acsmedchemlett.3c00303<\/a><\/p>\n\n\n\n

Moi, D.; Bonanni, D.; Belluti, S.; Linciano, P.; Citarella, A.; Franchini, S.; Sorbi, C.; Imbriano, C.; Pinzi, L.; Rastelli, G.
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer<\/strong>
(2023) European Journal of Medicinal Chemistry<\/em>, 260, 115730
DOI: 10.1016\/j.ejmech.2023.115730<\/a><\/a><\/p>\n\n\n\n

Rossino, G.; Marchese, E.; Galli, G.; Verde, F.; Finizio, M.; Serra, M.; Linciano, P.; Collina, S. 
Peptides as Therapeutic Agents: Challenges and Opportunities in the Green Transition Era<\/strong>
(2023) Molecules, <\/em>28<\/em>(20), 7165<\/em>
DOI: 10.3390\/molecules28207165<\/a><\/p>\n\n\n\n

Cavalloro, V.; Soddu, F.; Baroni, S.; Robustelli della Cuna, F.S.; Tavazzi, E.; Martino, E.; Collina, S. 
Teodorico Borgognoni\u2019s Formulary for Thirteenth Century Anesthetic Preparations<\/strong>
(2023) Life, <\/em>13<\/em>(9), 1913<\/em>
DOI: 10.3390\/life13091913<\/a><\/p>\n\n\n\n

D\u2019Amato, M.; Campagnoli, M.; Iadarola, P.; Bignami, P.M.; Fumagalli, M.; Chiarelli, L.R.; Stelitano, G.; Meloni, F.; Linciano, P.; Collina, S.; Pietrocola, G.; Vertuli, V.; Aliberti, A.; Fossali, T.; Viglio, S.
Could the Oxidation of \u03b11-Antitrypsin Prevent the Binding of Human Neutrophil Elastase in COVID-19 Patients?<\/strong>
(2023) Int. J. Mol. Sci.<\/em>, 24<\/em>(17), 13533<\/em><\/em>
DOI: 10.3390\/ijms241713533<\/a><\/p>\n\n\n\n

Marchesi, N.; Linciano, P.; Campagnoli, L.I.M.; Fahmideh, F.; Rossi, D.; Costa, G.; Ambrosio, F.A.; Barbieri, A.; Collina, S.; Pascale, A.
Short- and Long-Term Regulation of HuD: A Molecular Switch Mediated by Folic Acid?<\/strong>
(2023) Int. J. Mol. Sci.<\/em><\/em>, 24<\/em>(15), 12201<\/em><\/em>
DOI: 10.3390\/ijms241512201<\/a><\/p>\n\n\n\n

Rossino, G.; Marra, A.; Listro, R.; Peviani, M.; Poggio, E.; Curti, D.; Pellavio, G.; Laforenza, U.; Dondio, G.; Schepmann, D.; W\u00fcnsch, B.; Bedeschi, M.; Marino, N.; Tesei, A.; Ha, J.-J.; Kim, Y.-H.; Ann, J.; Lee, J.; Linciano, P.; Di Giacomo, M.; Rossi D.; Collina, S.
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain<\/strong>
(2023) Pharmaceuticals<\/em>, 16<\/em>(7), 962<\/em>
DOI: 10.3390\/ph16070962<\/a><\/p>\n\n\n\n

Linciano, P.; Sorbi, C.; Rossino, G.;  Rossi, D.; Marsala, A.; Denora, N.; Bedeschi, M.; Marino, N.; Miserocchi, G.; Dondio, G.; Peviani, M.; Tesei, A.; Collina, S.; Franchini S.
Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents<\/strong>
(2023) European Journal of Medicinal Chemistry, 249, 115163<\/em>
DOI: 10.1016\/j.ejmech.2023.115163<\/a><\/p>\n\n\n\n

Pagano, K.; Listro, R.;  Linciano, P.; Rossi, D.; Longhi, E.; Taraboletti, G.; Molinari, H.; Collina, S.; Ragona, L.
Identification of a novel extracellular inhibitor of FGF2\/FGFR signaling axis by combined Virtual Screening and NMR Spectroscopy approach<\/strong>
(2023) Bioorganic Chemistry, 106529<\/em>
DOI: 10.1016\/j.bioorg.2023.106529<\/a><\/p>\n\n\n\n

Alfano, A.I.; Pelliccia, S.; Rossino, G.; Chianese, O.; Summa, V.; Collina, S.; Brindisi, M.
Continuous-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds<\/strong>
(2023) ACS Med. Chem. Lett.14(3), 326\u2013337<\/em>
DOI: 10.1021\/acsmedchemlett.3c00010<\/a><\/p>\n\n\n\n

Alfano, A.I.; Pelliccia, S.; Rossino, G.; Chianese, O.; Summa, V.; Collina, S.; Brindisi, M.
Photo-Flow Technology for Chemical Rearrangements: A Powerful Tool to Generate Pharmaceutically Relevant Compounds<\/strong>
(2023) ACS Med. Chem. Lett.<\/em>
DOI: 10.1021\/acsmedchemlett.3c00072<\/a><\/p>\n\n\n\n

Listro, R.; Milli, G.; Pellegrini, A.; Motta, C.; Cavalloro, V.; Martino, E.; Kirchmair, J.; Pietrocola, G.; Rossi, D.; Linciano, P.; Collina, S.
Structural Insights into the Ligand\u2013LsrK Kinase Binding Mode: A Step Forward in the Discovery of Novel Antimicrobial Agents<\/strong>
(2023) Molecules<\/em>, 28<\/em>, 2542
DOI: 10.3390\/molecules28062542<\/a><\/p>\n\n\n\n

Listro, R., Malacrida, A., Ambrosio, F.A., Rossino, G., Di Giacomo, M., Cavalloro, V., Garbagnoli, M., Linciano, P., Rossi, D., Cavaletti, G., Costa, G., Alcaro, S., Miloso, M., Collina, S.
From Nature to Synthetic Compounds: Novel 1(N),2,3 Trisubstituted-5-oxopyrrolidines Targeting Multiple Myeloma Cells<\/strong>
(2022) International Journal of Molecular Science, 23(21), 13061.
DOI: 10.3390\/ijms232113061<\/a><\/p>\n\n\n\n

P\u00f6hner, I., Quotadamo, A., Panecka-Hofman, J., Luciani, R., Santucci, M., Linciano, P., Landi, G., Di Pisa, F., Dello Iacono, L., Pozzi, C., Mangani, S., Gul, S., Witt, G., Ellinger, B., Kuzikov, M., Santarem, N., Cordeiro-da-Silva, A., Costi, M.P., Venturelli, A., Wade, R.C.
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1.<\/strong>
(2022) Journal of Medicinal Chemistry, 65(13), pp. 9011\u20139033.
DOI: 10.1021\/acs.jmedchem.2c00232<\/a><\/p>\n\n\n\n

Maddalon, A., Masi, M., Iulini, M., Linciano, P., Galbiati, V., Marinovich, M., Racchi, M., Buoso, E., Corsini, E.
Effects of endocrine active contaminating pesticides on RACK1 expression and immunological consequences in THP-1 cells<\/strong>
(2022) Environmental Toxicology and Pharmacology, 95, art. no. 103971
DOI: 10.1016\/j.etap.2022.103971<\/a><\/p>\n\n\n\n

Cavalloro, V., Robustelli della Cuna, F.S., Quai, E., Preda, S., Bracco, F., Martino E., Collina S.
Walking around the Autonomous Province of Trento (Italy): An Ethnobotanical Investigation<\/strong>
(2022) Plants, 11(17), art. no. 2246.
DOI: 10.3390\/plants11172246<\/a><\/p>\n\n\n\n

Listro, R., Rossino, G., Piaggi, F., Sonekan, F. F., Rossi, D., Linciano, P., Collina, S.
Urea-Based Anticancer Agents. Exploring 100-Years of Research with an Eye to the Future.<\/strong>
(2022) Frontiers in Chemistry,<\/strong> 10, art. no. 995351.
DOI: 10.3389\/fchem.2022.995351<\/a><\/p>\n\n\n\n

Rossino, G., Robescu, M. S., Licastro, E., Tedesco, C., Martello, I., Maffei, L., Vincenti, G., Bavaro, T., Collina, S.
Biocatalysis: A Smart and Green Tool for the Preparation of Chiral Drugs<\/strong>
(2022) Chirality, 34(11), pp. 1403\u20131418. 
DOI: 10.1002\/chir.23498<\/a>.<\/p>\n\n\n\n

Martino, E., Granata, M.U., Catoni, R., Cavalloro, V.; Bracco, F.
New insight into pectin effects on mesophyll conductance in four species of deciduous Forest.<\/strong>
(2022) Natural product research, 36(17), art. no. 2246.
DOI: 10.1080\/14786419.2021.1990280<\/a><\/p>\n\n\n\n

Tesei, A., Cortesi, M., Bedeschi, M., Marino, N., Rossino, G., Listro, R., Rossi, D., Linciano, P., Collina, S.
Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer<\/strong>
(2022) Molecules, 27(14), art. no. 4327.
DOI: 10.3390\/molecules27144327<\/a>.<\/p>\n\n\n\n

Vigani, B., Valentino, C., Cavalloro, V., Catenacci, L., Sorrenti, M., Sandri, G., Bonferoni, M.C., Bozzi, C., Collina, S., Rossi, S., Franca Ferrari
Gellan-Based Composite System as a Potential Tool for the Treatment of Nervous Tissue Injuries: Cross-Linked Electrospun Nanofibers Embedded in a RC-33-Loaded Freeze-Dried Matrix<\/strong>
(2021) Pharmaceutics, 13(2), art. no. 164.
DOI: 10.3390\/pharmaceutics13020164<\/a><\/p>\n\n\n\n

Malacrida, A., Cavalloro, V., Martino, E., Costa, G., Ambrosio, F.A., Alcaro, S., Rigolio, R., Cassetti, A., Miloso, M., Collina, S.
Anti-Multiple Myeloma Potential of Secondary Metabolites from Hibiscus sabdariffa<\/em>\u2014Part 2.<\/strong>
(2021) Molecules, 26, art. no. 6596.
DOI: 10.3390\/molecules26216596<\/a><\/p>\n\n\n\n

Ambrosio, F.A., Coricello, A., Costa, G., Lupia, A., Micaelli, M., Marchesi, N., Sala, F., Pascale, A., Rossi, D., Vasile, F., Alcaro, S., Collina.
Identification of Compounds Targeting HuD. Another Brick in the Wall of Neurodegenerative Disease Treatment<\/strong>
(2021) Journal of Medicinal Chemistry, 64(14), 9989-10000.
DOI: 10.1021\/acs.jmedchem.1c00191<\/a><\/p>\n\n\n\n

Linciano, L., Nasti R., Listro R., Amadio, M, Pascale,A Potenza, D., Vasile, F. Minneci, M., Ann, J., Lee, J., Zhou, X., Mitchell, G.A., Blumberg, P.M., Rossi, D., Collina, S.
Chiral 2-phenyl-3- hydroxypropyl esters as PKC-alpha modulators. Hplc enantioseparation, NMR absolute configuration assignment and molecular docking studies<\/strong>
(2021) Chirality, 34(3), pp. 498-513.
DOI: 10.1002\/chir.23406<\/a><\/p>\n\n\n\n

Castelli, M., Serapian, S.A., Marchetti, F., Triveri, A., Pirota, V., Torielli, L., Collina, S., Doria, F., Freccero, M, Colombo, G.
New perspectives in cancer drug development: computational advances with an eye to design.<\/strong>
(2021) RSC Med. Chem., 12, pp. 1491-1502.
DOI: 10.1039\/D1MD00192B<\/a> <\/p>\n\n\n\n

Cavalloro, V., Marrubini, G., Stabile, R.; Rossi, D.; Linciano, P., Gheza, G., Assini S., Martino, E., Collina, S.
Microwave-Assisted Extraction and HPLC-UV-CD Determination of (S)-usnic Acid in Cladonia foliacea<\/em><\/strong>
(2021) Molecules, 26(2), art. no. 455.
DOI: 10.3390\/molecules26020455<\/a><\/p>\n\n\n\n

Rossino, G., Rui, M., Linciano, P., Rossi, D., Boiocchi, M., Peviani, M., Poggio, E., Curti, D., Schepmann, D., W\u00fcnsch, B., Gonz\u00e1lez-Avenda\u00f1o, M., Vergara-Jaque, A., Caballero, J., Collina, S.
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization.<\/strong>
(2021) Journal of Medicinal Chemistry, 64(20), pp. 14997\u201315016.
DOI: 10.1021\/acs.jmedchem.1c00886<\/a>.<\/p>\n\n\n\n

Granata, M.U., Bracco, F., Catoni, R., Cavalloro, V., Martino, E.
Secondary metabolites profile and physiological leaf traits in wild and cultivated Corylus avellana <\/em>under different nutritional status<\/em>.<\/strong>
(2021) Natural product and research, 35(18), pp. 3100-3107.
DOI: 10.1080\/14786419.2019.1682577<\/a><\/p>\n\n\n\n

Della Volpe, S., Linciano, P., Listro, R., Tumminelli, E., Amadio, M., Bonomo, I., Elgaher, W.A.M., Adam, S. , Hirsch, A.K.H., Boeckler, F.M. , Vasile, F., Rossi, D., Collina, S.
Identification of N,N- arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization<\/strong>
(2021) Bioorganic Chemistry, pp. 116.
DOI: 10.1016\/j.bioorg.2021.105305<\/a><\/p>\n\n\n\n

Vigani, B., Valentino, C., Sandri, G., Listro, R., Fagiani, F., Collina, S., Lanni, C., Bonferoni, M.C., Caramella, C.M., Rossi, S., Ferrari, F.
A Composite Nanosystem as a Potential Tool for the Local Treatment of Glioblastoma: Chitosan-Coated Solid Lipid Nanoparticles Embedded in Electrospun Nanofibers<\/strong>
(2021) Polymers, 13, ert. no. 1371.
DOI: 10.3390\/polym13091371<\/a><\/p>\n\n\n\n

Pellavio, G., Rossino, G., Gastaldi, G., Rossi, D., Linciano, P., Collina, S., Laforenza, U.
Sigma-1 Receptor Agonists Acting on Aquaporin-Mediated H2O2 Permeability: New Tools for Counteracting Oxidative Stress<\/strong>
(2021) International Journal of Molecular Science, 22(18), 9790.
DOI: 10.3390\/ijms22189790<\/a>.<\/p>\n\n\n\n

Auriemma, R., Sponchioni, M., Capasso Palmiero, U., Rossino, G., Rossetti, A., Marsala, A., Collina, S., Sacchetti, A., Moscatelli, D., Peviani, M.
Synthesis and Characterization of a \u201cClickable\u201d PBR28 TSPO-Selective Ligand Derivative Suitable for the Functionalization of Biodegradable Polymer Nanoparticles.<\/strong>
(2021) Nanomaterials, 11, 1693.
DOI: 10.3390\/nano11071693<\/a><\/p>\n\n\n\n

Linciano, P., Cavalloro, V., Martino, E., Kirchmair, J., Listro, R., Rossi, D., Collina, S.
Tackling Antimicrobial Resistance with Small Molecules Targeting LsrK: Challenges and Opportunities<\/strong>
(2020) Journal of Medicinal Chemistry, 63(24), pp. 15243- 15257.
DOI: 10.1021\/acs.jmedchem.0c01282<\/a><\/p>\n\n\n\n

Listro, R., Rossino, G., Della Volpe, S., Stabile, R., Boiocchi, M., Malavasi, L., Rossi, D., Collina, S.
Enantiomeric Resolution and Absolute Configuration of a Chiral \u03b4-Lactam, Useful Intermediate for the Synthesis of Bioactive Compounds.<\/strong>
(2020) Molecules, 25<\/em> (24), art. no. 6023.
DOI: 10.3390\/molecules25246023<\/a>.<\/p>\n\n\n\n

Cortesi, M., Zamagni, A., Pignatta, S., Zanoni, M., Arienti, C., Rossi, D., Collina, S., Tesei, A.
Pan-Sigma Receptor Modulator RC-106 Induces Terminal Unfolded Protein Response In In Vitro Pancreatic Cancer Model<\/strong>
(2020) Int. J. Mol. Sci., 21(23), art no. 9012.
DOI: 10.3390\/ijms21239012<\/a><\/p>\n\n\n\n

Linciano, P., Rossino, G., Listro, R., Rossi, D., Collina, S.
Sigma-1 Receptor Antagonists: Promising Players in Fighting Neuropathic Pain<\/strong>
(2020) Pharmaceutical Patent Analysis, 9 (3), pp. 77\u201385.
DOI: 10.4155\/ppa-2020-0007<\/a>.<\/p>\n\n\n\n

Rossino, G., Rui, M., Pozzetti, L., Schepmann, D., W\u00fcnsch, B., Zampieri, D., Pellavio, G., Laforenza, U., Rinaldi, S., Colombo, G., Morelli, L., Linciano, P., Rossi, D., Collina, S.
Setup and validation of a reliable docking protocol for the development of neuroprotective agents by targeting the sigma-1 receptor (S1R)<\/strong>
(2020) International Journal of Molecular Sciences, 21 (20), art. no. 7708, pp. 1-21.
DOI: 10.3390\/ijms21207708<\/a><\/p>\n\n\n\n

G\u00fctschow, M., Eynde, J.J.V., Jampilek, J., Kang, C., Mangoni, A.A., Fossa, P., Karaman, R., Trabocchi, A., Scott, P.J.H., Reynisson, J., Rapposelli, S., Galdier, S., Winum, J.-Y., Brullo, C., Prokai-Tatrai, K., Sharma, A.K., Schapira, M., Azuma, Y.-T., Cerchia, L., Spete, M., Torri, G., Collina, S., Geronikaki, A., Garc\u00eda-Sosa, A.T., Helena Vasconcelos, M., Sousa, M.E., Kosalec, I., Tuccinardi, T., Duarte, I.F., Salvador, J.A.R., Bertinaria, M., Pellecchia, M., Amato, J., Rastelli, G., Gomes, P.A.C., Guedes, R.C., Sabatier, J.-M., Est\u00e9vez-Braun, A., Pagano, B., Mangani, S., Ragno, R., Kokotos, G., Brindisi, M., Gonz\u00e1lez, F.V., Borges, F., Miloso, M., Rautio, J., Mu\u00f1oz-Torrero, D.
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-7<\/strong>
(2020) Molecules, 25 (13), art. no. 2968, .
DOI: 10.3390\/molecules25132968<\/a><\/p>\n\n\n\n

Listro, R., Stotani, S., Rossino, G., Rui, M., Malacrida, A., Cavaletti, G., Cortesi, M., Arienti, C., Tesei, A., Rossi, D., Giacomo, M.D., Miloso, M., Collina, S.
Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents<\/strong>
(2020) Frontiers in Chemistry, 8, art. no. 495, .
DOI: 10.3389\/fchem.2020.00495<\/a><\/p>\n\n\n\n

Volpe, S.D., Listro, R., Parafioriti, M., Di Giacomo, M., Rossi, D., Ambrosio, F.A., Costa, G., Alcaro, S., Ortuso, F., Hirsch, A.K.H., Vasile, F., Collina, S.
BOPC1 Enantiomers Preparation and HuR Interaction Study. From Molecular Modeling to a Curious DEEP-STD NMR Application<\/strong>
(2020) ACS Medicinal Chemistry Letters, 11 (5), pp. 883-888.
DOI: 10.1021\/acsmedchemlett.9b00659<\/a><\/p>\n\n\n\n

Distante, F., Collina, S., Quadrelli, P.
A practical synthesis of (3-(phenanthren-9-yl)-4,5-dihydroisoxazol-5-yl)methyl (tert-butoxycarbonyl)-L-alaninate<\/strong>
(2020) Arkivoc, 2020 (6), .
DOI: 10.24820\/ARK.5550190.P011.160dummy2<\/a><\/p>\n\n\n\n

Rossino, G., Orellana, I., Caballero, J., Schepmann, D., W\u00fcnsch, B., Rui, M., Rossi, D., Gonz\u00e1lez-Avenda\u00f1o, M., Collina, S., Vergara-Jaque, A.
New Insights into the Opening of the Occluded Ligand-Binding Pocket of Sigma1 Receptor: Binding of a Novel Bivalent RC-33 Derivative<\/strong>
(2020) Journal of Chemical Information and Modeling, 60 (2), pp. 756-765.
DOI: 10.1021\/acs.jcim.9b00649<\/a><\/p>\n\n\n\n

Cavalloro, V., Russo, K., Vasile, F., Pignataro, L., Torretta, A., Donini, S., Semrau, M.S., Storici, P., Rossi, D., Rapetti, F., Brullo, C., Parisini, E., Bruno, O., Collina, S.
Insight into GEBR-32a: Chiral resolution, absolute configuration and enantiopreference in PDE4D inhibition<\/strong>
(2020) Molecules, 25 (4), art. no. 935, .
DOI: 10.3390\/molecules25040935<\/a><\/p>\n\n\n\n

Cavalloro, V., Bracco, F., Collina, S., Martino, E.
A Focus on Phytochemical and Pharmacological Profile of Prunus lycioides<\/em> (=Amygdalus lycioides<\/em>).<\/strong>
(2020) Mini-review in medicinal chemistry, 20(20), pp. 2207-2214.
DOI: 10.2174\/1389557520666200730153653<\/a><\/p>\n\n\n\n

Senatore, R., Malik, M., Touqeer, S., Listro, R., Collina, S., Holzer, W., Pace, V.
Straightforward and direct access to \u03b2-seleno- amines and sulfonylamides via the controlled addition of phenylselenomethyllithium (LiCH2SePh) to imines
<\/strong>(2020) Tetrahedron, art. no. 131220, .
DOI: 10.1016\/j.tet.2020.131220<\/a><\/p>\n\n\n\n

Vigani, B., Rossi, S., Sandri, G., Bonferoni, M.C., Rui, M., Collina, S., Fagiani, F., Lanni, C., Ferrari, F.
Dual-functioning scaffolds for the treatment of spinal cord injury: Alginate nanofibers loaded with the sigma 1 receptor (S1R) Agonist RC-33 in chitosan films<\/strong>
(2020) Marine Drugs, 18 (1), art. no. 21, .
DOI: 10.3390\/md18010021<\/a><\/p>\n\n\n\n

Vanden Eynde, J.J., Mangoni, A.A., Rautio, J., Leprince, J., Azuma, Y.-T., Garc\u00eda-Sosa, A.T., Hulme, C., Jampilek, J., Karaman, R., Li, W., Gomes, P.A.C., Hadjipavlou-Litina, D., Capasso, R., Geronikaki, A., Cerchia, L., Sabatier, J.-M., Ragno, R., Tuccinardi, T., Trabocchi, A., Winum, J.-Y., Luque, F.J., Prokai-Tatrai, K., Spetea, M., G\u00fctschow, M., Kosalec, I., Guillou, C., Vasconcelos, M.H., Kokotos, G., Rastelli, G., De Sousa, M.E., Manera, C., Gemma, S., Mangani, S., Siciliano, C., Galdiero, S., Liu, H., Scott, P.J.H., De Los R\u00edos, C., Agrofoglio, L.A., Collina, S., Guedes, R.C., Mu\u00f1oz-Torrero, D.
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-6<\/strong>
(2020) Molecules, 25 (1), art. no. 119, .
DOI: 10.3390\/molecules25010119<\/a><\/p>\n\n\n\n

Zampieri, D., Fortuna, S., Calabretti, A., Romano, M., Menegazzi, R., Schepmann, D., W\u00fcnsch, B., Collina, S., Zanon, D., Mamolo, M.G.
Discovery of new potent dual sigma receptor\/GluN2b ligands with antioxidant property as neuroprotective agents<\/strong>
(2019) European Journal of Medicinal Chemistry, 180, pp. 268-282.
DOI: 10.1016\/j.ejmech.2019.07.012<\/a><\/p>\n\n\n\n

Vel\u00e1zquez-Libera, J.L., Rossino, G., Navarro-Retamal, C., Collina, S., Caballero, J.
Docking, Interaction Fingerprint, and Three-Dimensional Quantitative Structure\u2013Activity Relationship (3D-QSAR) of Sigma1 Receptor Ligands, Analogs of the Neuroprotective Agent RC-33<\/strong>
(2019) Frontiers in Chemistry, 7, art. no. 496, .
DOI: 10.3389\/fchem.2019.00496<\/a><\/p>\n\n\n\n

Martino, E., Della Volpe, S., Cavalloro, V., Amri, B., Kaab, L.B.B., Marrubini, G., Rossi, D., Collina, S.
The use of a microwave-assisted solvent extraction coupled with HPLC-UV\/PAD to assess the quality of Marrubium vulgare<\/em> L. (white horehound) herbal raw material<\/strong>
(2019) Phytochemical Analysis, 30 (4), pp. 377-384.
DOI: 10.1002\/pca.2820<\/a><\/p>\n\n\n\n

Moiola, M., Crespi, S., Memeo, M., Collina, S., Overkleeft, H., Florea, B., Quadrelli, P.
Scope and Limitations of Boron Fluorescent Complexes from Stable Nitrile Oxides in ABPP Assays<\/strong>
(2019) ACS Omega, 4 (4), pp. 7766-7774.
DOI: 10.1021\/acsomega.9b00672<\/a><\/p>\n\n\n\n

Della Volpe, S., Nasti, R., Queirolo, M., Unver, M.Y., Jumde, V.K., D\u00f6mling, A., Vasile, F., Potenza, D., Ambrosio, F.A., Costa, G., Alcaro, S., Zucal, C., Provenzani, A., Di Giacomo, M., Rossi, D., Hirsch, A.K.H., Collina, S.
Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies<\/strong>
(2019) ACS Medicinal Chemistry Letters, 10 (4), pp. 615-620.
DOI: 10.1021\/acsmedchemlett.8b00600<\/a><\/p>\n\n\n\n

Vigani, B., Rossi, S., Gentile, M., Sandri, G., Bonferoni, M.C., Cavalloro, V., Martino, E., Collina, S., Ferrari, F.
Development of a mucoadhesive and an in situ gelling formulation based on \u03ba-carrageenan for application on oral mucosa and esophagus walls. II. Loading of a bioactive hydroalcoholic extract<\/strong>
(2019) Marine Drugs, 17 (3), art. no. 153, .
DOI: 10.3390\/md17030153<\/a><\/p>\n\n\n\n

Raimondi, M.V., Listro, R., Cusimano, M.G., La Franca, M., Faddetta, T., Gallo, G., Schillaci, D., Collina, S., Leonchiks, A., Barone, G.
Pyrrolomycins as antimicrobial agents. Microwave-assisted organic synthesis and insights into their antimicrobial mechanism of action<\/strong>
(2019) Bioorganic and Medicinal Chemistry, 27 (5), pp. 721-728.
DOI: 10.1016\/j.bmc.2019.01.010<\/a><\/p>\n\n\n\n

Rui, M., Rossino, G., Rossi, D., Collina, S.
CHAPTER 12: Sigma Receptors as New Target for Multiple Sclerosis<\/strong>
(2019) RSC Drug Discovery Series, 2019-January (70), pp. 264-284.
DOI: 10.1039\/9781788016070-00264<\/a><\/p>\n\n\n\n

Raimondi, M.V., Randazzo, O., Franca, M.L., Barone, G., Vignoni, E., Rossi, D., Collina, S.
DHFR inhibitors: Reading the past for discovering novel anticancer agents<\/strong>
(2019) Molecules, 24 (6), art. no. 1140, .
DOI: 10.3390\/molecules24061140<\/a><\/p>\n\n\n\n

Martino, E., Tarantino, M., Bergamini, M., Castelluccio, V., Coricello, A., Falcicchio, M., Lorusso, E., Collina, S.
Artemisinin and its derivatives; Ancient tradition inspiring the latest therapeutic approaches against malaria<\/strong>
(2019) Future Medicinal Chemistry, 11 (12), pp. 1443-1459.
DOI: 10.4155\/fmc-2018-0337<\/a><\/p>\n\n\n\n

Stotani, S., Gatta, V., Medarametla, P., Padmanaban, M., Karawajczyk, A., Giordanetto, F., Tammela, P., Laitinen, T., Poso, A., Tzalis, D., Collina, S.
DPD-Inspired Discovery of Novel LsrK Kinase Inhibitors: An Opportunity to Fight Antimicrobial Resistance<\/strong>
(2019) Journal of Medicinal Chemistry, .
DOI: 10.1021\/acs.jmedchem.9b00025<\/a><\/p>\n\n\n\n

Malacrida, A., Cavalloro, V., Martino, E., Cassetti, A., Nicolini, G., Rigolio, R., Cavaletti, G., Mannucci, B., Vasile, F., Di Giacomo, M., Collina, S., Miloso, M.
Anti-multiple myeloma potential of secondary metabolites from Hibiscus sabdariffa<\/em><\/strong>
(2019) Molecules, 24 (13), art. no. 2500, .
DOI: 10.3390\/molecules24132500<\/a><\/p>\n\n\n\n

Tesei, A., Cortesi, M., Pignatta, S., Arienti, C., Massimo Dondio, G., Bigogno, C., Malacrida, A., Miloso, M., Meregalli, C., Chiorazzi, A., Carozzi, V., Cavaletti, G., Rui, M., Marra, A., Rossi, D., Collina, S.
Anti-tumor efficacy assessment of the sigma receptor pan modulator RC-106. A promising therapeutic tool for pancreatic cancer<\/strong>
(2019) Frontiers in Pharmacology, 10 (MAY), art. no. 490, .
DOI: 10.3389\/fphar.2019.00490<\/a><\/p>\n\n\n\n

Mangoni, A.A., Guillou, C., Eynde, J.J.V., Hulme, C., Jampilek, J., Li, W., Prokai-Tatrai, K., Rautio, J., Collina, S., Tuccinardi, T., Sousa, M.E., Sabatier, J.-M., Galdiero, S., Karaman, R., Kokotos, G., Torri, G., Javier Luque, F., Helena Vasconcelos, M., Hadjipavlou-Litina, D., Siciliano, C., G\u00fctschow, M., Ragno, R., Gomes, P.A.C., Agrofoglio, L.A., Mu\u00f1oz-Torrero, D.
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-4<\/strong>
(2019) Molecules, 24 (1), pp. 1-12.
DOI: 10.3390\/molecules24010130<\/p>\n\n\n\n

Mangoni, A.A., Eynde, J.J.V., Jampilek, J., Hadjipavlou-Litina, D., Liu, H., Reynisson, J., Sousa, M.E., Gomes, P.A.C., Prokai-Tatrai, K., Tuccinardi, T., Sabatier, J.-M., Luque, F.J., Rautio, J., Karaman, R., Vasconcelos, M.H., Gemma, S., Galdiero, S., Hulme, C., Collina, S., G\u00fctschow, M., Kokotos, G., Siciliano, C., Capasso, R., Agrofoglio, L.A., Ragno, R., Mu\u00f1oz-Torrero, D.
Breakthroughs in medicinal chemistry: New targets and mechanisms, New Drugs, New Hopes-5<\/strong>
(2019) Molecules, 24 (13), art. no. 2415, .
DOI: 10.3390\/molecules24132415<\/p>\n\n\n\n

Vasile, F., Della Volpe, S., Ambrosio, F.A., Costa, G., Unver, M.Y., Zucal, C., Rossi, D., Martino, E., Provenzani, A., Hirsch, A.K.H., Alcaro, S., Potenza, D., Collina, S.
Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approach<\/strong>
(2018) Scientific Reports, 8 (1), art. no. 13780, .
DOI: 10.1038\/s41598-018-32084-z<\/a><\/p>\n\n\n\n

Stotani, S., Gatta, V., Medda, F., Padmanaban, M., Karawajczyk, A., Tammela, P., Giordanetto, F., Tzalis, D., Collina, S.
A versatile strategy for the synthesis of 4,5-dihydroxy-2,3-pentanedione (DPD) and related compounds as potential modulators of bacterial quorum sensing<\/strong>
(2018) Molecules, 23 (10), art. no. 2545, .
DOI: 10.3390\/molecules23102545<\/a><\/p>\n\n\n\n

Rui, M., Rossino, G., Coniglio, S., Monteleone, S., Scuteri, A., Malacrida, A., Rossi, D., Catenacci, L., Sorrenti, M., Paolillo, M., Curti, D., Venturini, L., Schepmann, D., W\u00fcnsch, B., Liedl, K.R., Cavaletti, G., Pace, V., Urban, E., Collina, S.
Identification of dual Sigma1 receptor modulators\/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents<\/strong>
(2018) European Journal of Medicinal Chemistry, 158, pp. 353-370.
DOI: 10.1016\/j.ejmech.2018.09.010<\/a><\/p>\n\n\n\n

Martino, E., Casamassima, G., Castiglione, S., Cellupica, E., Pantalone, S., Papagni, F., Rui, M., Siciliano, A.M., Collina, S.
Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead<\/strong>
(2018) Bioorganic and Medicinal Chemistry Letters, 28 (17), pp. 2816-2826.
DOI: 10.1016\/j.bmcl.2018.06.044<\/a><\/p>\n\n\n\n

Tesei, A., Cortesi, M., Zamagni, A., Arienti, C., Pignatta, S., Zanoni, M., Paolillo, M., Curti, D., Rui, M., Rossi, D., Collina, S.
Sigma receptors as endoplasmic reticulum stress “gatekeepers” and their modulators as emerging new weapons in the fight against cancer<\/strong>
(2018) Frontiers in Pharmacology, 9 (JUN), art. no. 711, .
DOI: 10.3389\/fphar.2018.00711<\/a><\/p>\n\n\n\n

Rivara, S., Scalvini, L., Lodola, A., Mor, M., Caignard, D.-H., Delagrange, P., Collina, S., Lucini, V., Scaglione, F., Furiassi, L., Mari, M., Lucarini, S., Bedini, A., Spadoni, G.
Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands<\/strong>
(2018) Journal of Medicinal Chemistry, 61 (8), pp. 3726-3737.
DOI: 10.1021\/acs.jmedchem.8b00359<\/a><\/p>\n\n\n\n

Rossino, G., Raimondi, M.V., Rui, M., Di Giacomo, M., Rossi, D., Collina, S.
PEG 400\/cerium ammonium nitrate combined with microwave-assisted synthesis for rapid access to beta-amino ketones. an easy-to-use protocol for discovering new hit compounds<\/strong>
(2018) Molecules, 23 (4), art. no. 775, .
DOI: 10.3390\/molecules23040775<\/a><\/p>\n\n\n\n

Cosimelli, B., Greco, G., Laneri, S., Novellino, E., Sacchi, A., Collina, S., Rossi, D., Cosconati, S., Barresi, E., Taliani, S., Trincavelli, M.L., Martini, C.
Studies on enantioselectivity of chiral 4-acetylamino-6-alkyloxy-2-alkylthiopyrimidines acting as antagonists of the human A3 adenosine receptor<\/strong>
(2018) MedChemComm, 9 (1), pp. 81-86.
DOI: 10.1039\/c7md00375g<\/a><\/p>\n\n\n\n

Mu\u00f1oz-Torrero, D., Mangoni, A.A., Liu, H., Hulme, C., Rautio, J., Karaman, R., De Sousa, M.E., Prokai-Tatrai, K., Sabatier, J.-M., Siciliano, C., Luque, F.J., Kokotos, G., Ragno, R., Collina, S., Guillou, C., Tschow, M.G., Agrofoglio, L.A.
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes\u20132<\/strong>
(2018) Molecules, 23 (1), art. no. 65, .
DOI: 10.3390\/molecules23010065<\/p>\n\n\n\n

Mangoni, A.A., Tuccinardi, T., Collina, S., Vanden Eynde, J.J., Mu oz-Torrero, D., Karaman, R., Siciliano, C., Em\u00edlia de Sousa, M., Prokai-Tatrai, K., Rautio, J., Guillou, C., G tschow, M., Galdiero, S., Liu, H., Agrofoglio, L.A., Sabatier, J.-M., Hulme, C., Kokotos, G., You, Q., Gomes, P.A.C.
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-3<\/strong>
(2018) Molecules, 23 (7), art. no. 1596, .
DOI: 10.3390\/molecules23071596<\/p>\n\n\n\n

Pellavio, G., Rui, M., Caliogna, L., Martino, E., Gastaldi, G., Collina, S., Laforenza, U.
Regulation of aquaporin functional properties mediated by the antioxidant effects of natural compounds<\/strong>
(2017) International Journal of Molecular Sciences, 18 (12), art. no. 2665, .
DOI: 10.3390\/ijms18122665<\/a><\/p>\n\n\n\n

Rossi, D., Tarantino, M., Rossino, G., Rui, M., Juza, M., Collina, S.
Approaches for multi-gram scale isolation of enantiomers for drug discovery<\/strong>
(2017) Expert Opinion on Drug Discovery, 12 (12), pp. 1253-1269.
DOI: 10.1080\/17460441.2017.1383981<\/a><\/p>\n\n\n\n

Collina, S., Rui, M., Stotani, S., Bignardi, E., Rossi, D., Curti, D., Giordanetto, F., Malacrida, A., Scuteri, A., Cavaletti, G.
Are sigma receptor modulators a weapon against multiple sclerosis disease?<\/strong>
(2017) Future Medicinal Chemistry, 9 (17), pp. 2029-2051.
DOI: 10.4155\/fmc-2017-0122<\/a><\/p>\n\n\n\n

Amri, B., Martino, E., Vitulo, F., Corana, F., Ben-Ka\u00e2b, L.B., Rui, M., Rossi, D., Mori, M., Rossi, S., Collina, S.
Marrubium vulgare<\/em> L. leave extract: Phytochemical composition, antioxidant and wound healing properties<\/strong>
(2017) Molecules, 22 (11), art. no. 1851, .
DOI: 10.3390\/molecules22111851<\/a><\/p>\n\n\n\n

Nasti, R., Rossi, D., Amadio, M., Pascale, A., Unver, M.Y., Hirsch, A.K.H., Collina, S.
Compounds Interfering with Embryonic Lethal Abnormal Vision (ELAV) Protein-RNA Complexes: An Avenue for Discovering New Drugs<\/strong>
(2017) Journal of Medicinal Chemistry, 60 (20), pp. 8257-8267.
DOI: 10.1021\/acs.jmedchem.6b01871<\/a><\/p>\n\n\n\n

Rossi, D., Nasti, R., Collina, S., Mazzeo, G., Ghidinelli, S., Longhi, G., Memo, M., Abbate, S.
The role of chirality in a set of key intermediates of pharmaceutical interest, 3-aryl-substituted-\u03b3-butyrolactones, evidenced by chiral HPLC separation and by chiroptical spectroscopies<\/strong>
(2017) Journal of Pharmaceutical and Biomedical Analysis, 144, pp. 41-51.
DOI: 10.1016\/j.jpba.2017.01.007<\/a><\/p>\n\n\n\n

Amri, B., Kaab, S.B., Gouia, H., Martino, E., Collina, S., Ka\u00e2b, L.B.B.
Copper-induced changes in nutrient uptake, enzymatic and non-enzymatic antioxidant systems in horehound (Marrubium vulgare<\/em> L.)<\/strong>
(2017) Botanical Sciences, 95 (3), pp. 565-575.
DOI: 10.17129\/botsci.778<\/p>\n\n\n\n

Rui, M., Nasti, R., Bignardi, E., Volpe, S.D., Rossino, G., Rossi, D., Collina, S.
PKC in regenerative therapy: New insights for old targets<\/strong>
(2017) Pharmaceuticals, 10 (2), art. no. 46, .
DOI: 10.3390\/ph10020046<\/a><\/p>\n\n\n\n

Pace, V., Castoldi, L., Monticelli, S., Rui, M., Collina, S.
New Perspectives in Lithium Carbenoid Mediated Homologations<\/strong>
(2017) Synlett, 28 (8), art. no. st-2016-p0838-sp, pp. 879-888.
DOI: 10.1055\/s-0036-1588139<\/a><\/p>\n\n\n\n

Collina, S., Bignardi, E., Rui, M., Rossi, D., Gaggeri, R., Zamagni, A., Cortesi, M., Tesei, A.
Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016)<\/strong>
(2017) Expert Opinion on Therapeutic Patents, 27 (5), pp. 565-578.
DOI: 10.1080\/13543776.2017.1276569<\/a><\/p>\n\n\n\n

Mu\u00f1oz-Torrero, D., Mangoni, A.A., Guillou, C., Collina, S., Eynde, J.J.V., Rautio, J., Keseru, G.M., Hulme, C., Chibale, K., Luque, F.J., Karaman, R., G\u00fctschow, M., Liu, H., Ragno, R.
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes<\/strong>
(2017) Molecules, 22 (5), art. no. 743, .
DOI: 10.3390\/molecules22050743<\/p>\n\n\n\n

Rossi, D., Ahmed, K.M., Gaggeri, R., Volpe, S.D., Maggi, L., Mazzeo, G., Longhi, G., Abbate, S., Corana, F., Martino, E., Machado, M., Varandas, R., Do C\u00e9u Sousa, M., Collina, S.
(R)-(-)-Aloesaponol III 8-methyl ether from Eremurus persicus<\/em>: A novel compound against leishmaniosis<\/strong>
(2017) Molecules, 22 (4), art. no. 519, .
DOI: 10.3390\/molecules22040519<\/a><\/p>\n\n\n\n

Curti, V., Di Lorenzo, A., Rossi, D., Martino, E., Capelli, E., Collina, S., Daglia, M.
Enantioselective modulatory effects of naringenin enantiomers on the expression levels of miR-17-3p involved in endogenous antioxidant defenses<\/strong>
(2017) Nutrients, 9 (3), art. no. 215, .
DOI: 10.3390\/nu9030215<\/a><\/p>\n\n\n\n

Dichiara, M., Marrazzo, A., Prezzavento, O., Collina, S., Rescifina, A., Amata, E.
Repurposing of Human Kinase Inhibitors in Neglected Protozoan Diseases<\/strong>
(2017) ChemMedChem, 12 (16), pp. 1235-1253.
DOI: 10.1002\/cmdc.201700259<\/a><\/p>\n\n\n\n

Martino, E., Della Volpe, S., Terribile, E., Benetti, E., Sakaj, M., Centamore, A., Sala, A., Collina, S.
The long story of camptothecin: From traditional medicine to drugs<\/strong>
(2017) Bioorganic and Medicinal Chemistry Letters, 27 (4), pp. 701-707.
DOI: 10.1016\/j.bmcl.2016.12.085<\/a><\/p>\n\n\n\n

Rossi, D., Rui, M., Di Giacomo, M., Schepmann, D., W\u00fcnsch, B., Monteleone, S., Liedl, K.R., Collina, S.
Gaining in pan-affinity towards sigma 1 and sigma 2 receptors. SAR studies on arylalkylamines<\/strong>
(2017) Bioorganic and Medicinal Chemistry, 25 (1), pp. 11-19.
DOI: 10.1016\/j.bmc.2016.10.005<\/a><\/p>\n\n\n\n

Rui, M., Marra, A., Pace, V., Juza, M., Rossi, D., Collina, S.
Novel enantiopure sigma receptor modulators: Quick (semi-)preparative chiral resolution via hplc and absolute configuration assignment<\/strong>
(2016) Molecules, 21 (9), art. no. 1210, .
DOI: 10.3390\/molecules21091210<\/a><\/p>\n\n\n\n

Shah, M.R., Ishtiaq, Hizbullah, S.M., Habtemariam, S., Zarrelli, A., Muhammad, A., Collina, S., Khan, I.
Protein tyrosine phosphatase 1B inhibitors isolated from Artemisia roxburghiana<\/strong>
(2016) Journal of Enzyme Inhibition and Medicinal Chemistry, 31 (4), pp. 563-567.
DOI: 10.3109\/14756366.2015.1047358<\/a><\/p>\n\n\n\n

Marra, A., Rossi, D., Maggi, L., Corana, F., Mannucci, B., Peviani, M., Curti, D., Collina, S.
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists<\/strong>
(2016) Biomedical Chromatography, 30 (4), pp. 645-651.
DOI: 10.1002\/bmc.3609<\/a><\/p>\n\n\n\n

Marra, A., Rossi, D., Pignataro, L., Bigogno, C., Canta, A., Oggioni, N., Malacrida, A., Corbo, M., Cavaletti, G., Peviani, M., Curti, D., Dondio, G., Collina, S.
Toward the identification of neuroprotective agents: G-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist<\/strong>
(2016) Future Medicinal Chemistry, 8 (3), pp. 287-295.
DOI: 10.4155\/fmc.15.191<\/a><\/p>\n\n\n\n

Rossi, D., Marra, A., Rui, M., Brambilla, S., Juza, M., Collina, S.
“Fit-for-purpose” development of analytical and (semi)preparative enantioselective high performance liquid and supercritical fluid chromatography for the access to a novel \u03c31 receptor agonist<\/strong>
(2016) Journal of Pharmaceutical and Biomedical Analysis, 118, pp. 363-369.
DOI: 10.1016\/j.jpba.2015.10.047<\/a><\/p>\n\n\n\n

Rossi, D., Nasti, R., Marra, A., Meneghini, S., Mazzeo, G., Longhi, G., Memo, M., Cosimelli, B., Greco, G., Novellino, E., Da Settimo, F., Martini, C., Taliani, S., Abbate, S., Collina, S.
Enantiomeric 4-Acylamino-6-alkyloxy-2 Alkylthiopyrimidines As Potential A3Adenosine Receptor Antagonists: HPLC Chiral Resolution and Absolute Configuration Assignment by a Full Set of Chiroptical Spectroscopy<\/strong>
(2016) Chirality, 28 (5), pp. 434-440.
DOI: 10.1002\/chir.22599<\/a><\/p>\n\n\n\n

Rui, M., Rossi, D., Marra, A., Paolillo, M., Schinelli, S., Curti, D., Tesei, A., Cortesi, M., Zamagni, A., Laurini, E., Pricl, S., Schepmann, D., W\u0171nsch, B., Urban, E., Pace, V., Collina, S.
Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents<\/strong>
(2016) European Journal of Medicinal Chemistry, 124, pp. 649-665.
DOI: 10.1016\/j.ejmech.2016.08.067<\/a><\/p>\n\n\n\n

Rossi, D., Talman, V., Genn\u00e4s, G.B.A., Marra, A., Picconi, P., Nasti, R., Serra, M., Ann, J., Amadio, M., Pascale, A., Tuominen, R.K., Yli-Kauhaluoma, J., Lee, J., Collina, S.
Beyond the affinity for protein kinase C: Exploring 2-phenyl-3-hydroxypropyl pivalate analogues as C1 domain-targeting ligands<\/strong>
(2015) MedChemComm, 6 (4), pp. 547-554.
DOI: 10.1039\/C4MD00564C<\/a><\/p>\n\n\n\n

Quesada-Romero, L., Mena-Ulecia, K., Zu\u00f1iga, M., De-la-Torre, P., Rossi, D., Tiznado, W., Collina, S., Caballero, J.
Optimal graph-based and simplified molecular input line entry system-based descriptors for quantitative structure-activity relationship analysis of arylalkylaminoalcohols, arylalkenylamines, and arylalkylamines as \u03c31 receptor ligands<\/strong>
(2015) Journal of Chemometrics, 29 (1), pp. 13-20.
DOI: 10.1002\/cem.2650<\/a><\/p>\n\n\n\n

Rossi, D., Marra, A., Rui, M., Laurini, E., Fermeglia, M., Pricl, S., Schepmann, D., Wuensch, B., Peviani, M., Curti, D., Collina, S.
A step forward in the sigma enigma: A role for chirality in the sigma1 receptor-ligand interaction?<\/strong>
(2015) MedChemComm, 6 (1), pp. 138-146.
DOI: 10.1039\/c4md00349g<\/a><\/p>\n\n\n\n

Vasile, F., Rossi, D., Collina, S., Potenza, D.
Diffusion-ordered spectroscopy and saturation transfer difference NMR spectroscopy studies of selective interactions between ELAV protein fragments and an mRNA target<\/strong>
(2014) European Journal of Organic Chemistry, 2014 (29), pp. 6399-6404.
DOI: 10.1002\/ejoc.201403014<\/a><\/p>\n\n\n\n

Chlapanidas, T., Perteghella, S., Leoni, F., Farag\u00f2, S., Marazzi, M., Rossi, D., Martino, E., Gaggeri, R., Collina, S.
TNF-\u03b1 blocker effect of naringenin-loaded sericin microparticles that are potentially useful in the treatment of psoriasis<\/strong>
(2014) International Journal of Molecular Sciences, 15 (8), pp. 13624-13636.
DOI: 10.3390\/ijms150813624<\/a><\/p>\n\n\n\n

Cateni, F., Zilic, J., Altieri, T., Zacchigna, M., Procida, G., Gaggeri, R., Rossi, D., Collina, S.
Lipid metabolites with free-radical scavenging activity from Euphorbia helioscopia<\/em> L.<\/strong>
(2014) Chemistry and Physics of Lipids, 181, pp. 90-98.
DOI: 10.1016\/j.chemphyslip.2014.03.001<\/a><\/p>\n\n\n\n

Peviani, M., Salvaneschi, E., Bontempi, L., Petese, A., Manzo, A., Rossi, D., Salmona, M., Collina, S., Bigini, P., Curti, D.
Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation<\/strong>
(2014) Neurobiology of Disease, 62, pp. 218-232.
DOI: 10.1016\/j.nbd.2013.10.010<\/a><\/p>\n\n\n\n

Lucconi, G., Chlapanidas, T., Martino, E., Gaggeri, R., Perteghella, S., Rossi, D., Farag\u00f2, S., Vigo, D., Faustini, M., Collina, S., Torre, M.L.
Formulation of microspheres containing Crataegus monogyna Jacq. extract with free radical scavenging activity<\/strong>
(2014) Pharmaceutical Development and Technology, 19 (1), pp. 65-72.
DOI: 10.3109\/10837450.2012.752387<\/a><\/p>\n\n\n\n

Rossi, D., Pedrali, A., Marra, A., Pignataro, L., Schepmann, D., W\u00fcnsch, B., Ye, L., Leuner, K., Peviani, M., Curti, D., Azzolina, O., Collina, S.
Studies on the Enantiomers of RC-33 as Neuroprotective Agents: Isolation, Configurational Assignment, and Preliminary Biological Profile<\/strong>
(2013) Chirality, 25 (11), pp. 814-822.
DOI: 10.1002\/chir.22223<\/a><\/p>\n\n\n\n

Rossi, D., Pedrali, A., Gaggeri, R., Marra, A., Pignataro, L., Laurini, E., DalCol, V., Fermeglia, M., Pricl, S., Schepmann, D., W\u00fcnsch, B., Peviani, M., Curti, D., Collina, S.
Chemical, pharmacological, and in vitro metabolic stability studies on enantiomerically pure RC-33 compounds: Promising neuroprotective agents acting as \u03c31 receptor agonists<\/strong>
(2013) ChemMedChem, 8 (9), pp. 1514-1527.
DOI: 10.1002\/cmdc.201300218<\/a><\/p>\n\n\n\n

Gaggeri, R., Rossi, D., Daglia, M., Leoni, F., Avanzini, M.A., Mantelli, M., Juza, M., Collina, S.
An eco-friendly enantioselective access to (R)-naringenin as inhibitor of proinflammatory cytokine release<\/strong>
(2013) Chemistry and Biodiversity, 10 (8), pp. 1531-1538.
DOI: 10.1002\/cbdv.201200227<\/p>\n\n\n\n

Talman, V., Amadio, M., Osera, C., Sorvari, S., Boije Af Genn\u00e4s, G., Yli-Kauhaluoma, J., Rossi, D., Govoni, S., Collina, S., Ekokoski, E., Tuominen, R.K., Pascale, A.
The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKC\u03b1 activation in SH-SY5Y cells<\/strong>
(2013) Pharmacological Research, 73, pp. 44-54.
DOI: 10.1016\/j.phrs.2013.04.008<\/a><\/p>\n\n\n\n

Amadio, M., Pascale, A., Govoni, S., Laurini, E., Pricl, S., Gaggeri, R., Rossi, D., Collina, S.
Identification of peptides with ELAV-like mRNA-stabilizing effect: An integrated in vitro\/in silico approach<\/strong>
(2013) Chemical Biology and Drug Design, 81 (6), pp. 707-714.
DOI: 10.1111\/cbdd.12117<\/a><\/p>\n\n\n\n

Collina, S., Gaggeri, R., Marra, A., Bassi, A., Negrinotti, S., Negri, F., Rossi, D.
Sigma receptor modulators: A patent review<\/strong>
(2013) Expert Opinion on Therapeutic Patents, 23 (5), pp. 597-613.
DOI: 10.1517\/13543776.2013.769522<\/a><\/p>\n\n\n\n

Rossi, D., Marra, A., Picconi, P., Serra, M., Catenacci, L., Sorrenti, M., Laurini, E., Fermeglia, M., Pricl, S., Brambilla, S., Almirante, N., Peviani, M., Curti, D., Collina, S.
Identification of RC-33 as a potent and selective \u03c31 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: G-Scale synthesis, physicochemical characterization and in vitro metabolic stability<\/strong>
(2013) Bioorganic and Medicinal Chemistry, 21 (9), pp. 2577-2586.
DOI: 10.1016\/j.bmc.2013.02.029<\/a><\/p>\n\n\n\n

Daglia, M., Ferrari, D., Collina, S., Curti, V.
Influence of in vitro simulated gastroduodenal digestion on methylglyoxal concentration of manuka (Lectospermum scoparium) honey<\/strong>
(2013) Journal of Agricultural and Food Chemistry, 61 (9), pp. 2140-2145.
DOI: 10.1021\/jf304299d<\/a><\/p>\n\n\n\n

Uddin, G., Rauf, A., Al-Othman, A.M., Collina, S., Arfan, M., Ali, G., Khan, I.
Pistagremic acid, a glucosidase inhibitor from Pistacia integerrima<\/em><\/strong>
(2012) Fitoterapia, 83 (8), pp. 1648-1652.
DOI: 10.1016\/j.fitote.2012.09.017<\/a><\/p>\n\n\n\n

Caballero, J., Zilocchi, S., Tiznado, W., Collina, S.
Docking and quantitative structure-activity relationship studies for imidazo[1,2-a]pyrazines as inhibitors of checkpoint kinase-1<\/strong>
(2012) Medicinal Chemistry Research, 21 (8), pp. 1912-1920.
DOI: 10.1007\/s00044-011-9714-1<\/a><\/p>\n\n\n\n

Caballero, J., Zilocchi, S., Tiznado, W., Rossi, D., Collina, S.
Models of the pharmacophoric pattern and affinity trend of methyl 2-(aminomethyl)-1-phenylcyclopropane-1-carboxylate derivatives as \u03c3 1 ligands<\/strong>
(2012) Molecular Simulation, 38 (3), pp. 227-235.
DOI: 10.1080\/08927022.2011.614243<\/a><\/p>\n\n\n\n

Gaggeri, R., Rossi, D., Christodoulou, M.S., Passarella, D., Leoni, F., Azzolina, O., Collina, S.
Chiral flavanones from Amygdalus lycioides<\/em> Spach: Structural elucidation and identification of TNFalpha inhibitors by bioactivity-guided fractionation<\/strong>
(2012) Molecules, 17 (2), pp. 1665-1674.
DOI: 10.3390\/molecules17021665<\/a><\/p>\n\n\n\n

Rossi, D., Pedrali, A., Urbano, M., Gaggeri, R., Serra, M., Fern\u00e1ndez, L., Fern\u00e1ndez, M., Caballero, J., Ronsisvalle, S., Prezzavento, O., Schepmann, D., Wuensch, B., Peviani, M., Curti, D., Azzolina, O., Collina, S.
Identification of a potent and selective \u03c11 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells<\/strong>
(2011) Bioorganic and Medicinal Chemistry, 19 (21), pp. 6210-6224.
DOI: 10.1016\/j.bmc.2011.09.016<\/a><\/p>\n\n\n\n

Caballero, J., Zilocchi, S., Tiznado, W., Collina, S., Rossi, D.
Binding Studies and Quantitative Structure-Activity Relationship of 3-Amino-1H-Indazoles as Inhibitors of GSK3\u03b2<\/strong>
(2011) Chemical Biology and Drug Design, 78 (4), pp. 631-641.
DOI: 10.1111\/j.1747-0285.2011.01186.x<\/a><\/p>\n\n\n\n

Gaggeri, R., Rossi, D., Collina, S., Mannucci, B., Baierl, M., Juza, M.
Quick development of an analytical enantioselective high performance liquid chromatography separation and preparative scale-up for the flavonoid naringenin<\/strong>
(2011) Journal of Chromatography A, 1218 (32), pp. 5414-5422.
DOI: 10.1016\/j.chroma.2011.02.038<\/a><\/p>\n\n\n\n

Rossi, D., Baraglia, A.C., Serra, M., Azzolina, O., Collina, S.
An efficient procedure based on a MW-assisted Horner-Wadsworth-Emmons reaction for the synthesis of (Z)-3,3-trisubstituted-\u03b1,\u03b2-unsaturated esters<\/strong>
(2010) Molecules, 15 (9), pp. 5928-5942.
DOI: 10.3390\/molecules15095928<\/a><\/p>\n\n\n\n

Rossi, D., Urbano, M., Pedrali, A., Serra, M., Zampieri, D., Mamolo, M.G., Laggner, C., Zanette, C., Florio, C., Schepmann, D., Wuensch, B., Azzolina, O., Collina, S.
Design, synthesis and SAR analysis of novel selective \u03c31 ligands (Part 2)<\/strong>
(2010) Bioorganic and Medicinal Chemistry, 18 (3), pp. 1204-1212.
DOI: 10.1016\/j.bmc.2009.12.039<\/a><\/p>\n\n\n\n

Rossi, D., Amadio, M., Baraglia, A.C., Azzolina, O., Ratti, A., Govoni, S., Pascale, A., Collina, S.
Discovery of small peptides derived from embryonic lethal abnormal vision proteins structure showing RNA-stabilizing properties<\/strong>
(2009) Journal of Medicinal Chemistry, 52 (16), pp. 5017-5019.
DOI: 10.1021\/jm900741e<\/a><\/p>\n\n\n\n

Comini, M., Pozzoli, C., Incerti, M., Rossi, D., Collina, S., Azzolina, O., di Vittorio, E., Morini, G., Poli, E.
Stereospecific effects of benzo[d]isothiazolyloxypropanolamine derivatives at \u03b2-adrenoceptors: Synthesis, chiral resolution, and biological activity in vitro<\/strong>
(2009) Chirality, 21 (2), pp. 284-291.
DOI: 10.1002\/chir.20574<\/a><\/p>\n\n\n\n

Rossi, D., Urbano, M., Baraglia, A.C., Serra, M., Bergamelli, F., Iannelli, M., Azzolina, O., Collina, S.
Polymer-assisted solution-phase synthesis under combined ultrasound and microwave irradiation: Preparation of \u03b1,\u03b2-unsaturated esters and carboxylic acids, key intermediates of novel sigma ligands<\/strong>
(2009) Synthetic Communications, 39 (18), pp. 3254-3262.
DOI: 10.1080\/00397910902738112<\/a><\/p>\n\n\n\n

Zampieri, D., Grazia Mamolo, M., Laurini, E., Zanette, C., Florio, C., Collina, S., Rossi, D., Azzolina, O., Vio, L.
Substituted benzo[d]oxazol-2(3H)-one derivatives with preference for the \u03c31 binding site<\/strong>
(2009) European Journal of Medicinal Chemistry, 44 (1), pp. 124-130.
DOI: 10.1016\/j.ejmech.2008.03.011<\/a><\/p>\n\n\n\n

Martino, E., Collina, S., Rossi, D., Bazzoni, D., Gaggeri, R., Bracco, F., Azzolina, O.
Influence of the extraction mode on the yield of hyperoside, vitexin and vitexin-2-O-rhamnoside from Crataegus monogyna<\/em> Jacq. (Hawthorn)<\/strong>
(2008) Phytochemical Analysis, 19 (6), pp. 534-540.
DOI: 10.1002\/pca.1081<\/a><\/p>\n\n\n\n

Mamolo, M.G., Zampieri, D., Zanette, C., Florio, C., Collina, S., Urbano, M., Azzolina, O., Vio, L.
Substituted benzylaminoalkylindoles with preference for the \u03c32 binding site<\/strong>
(2008) European Journal of Medicinal Chemistry, 43 (10), pp. 2073-2081.
DOI: 10.1016\/j.ejmech.2007.09.012<\/a><\/p>\n\n\n\n

Urbano, M., Collina, S., Rossi, D., Carnevale Baraglia, A., Alcaro, S., Artese, A., Azzolina, O.
Design and synthesis of a (N-alkylaminoalkyl-substituted)arylalkenylamide drug discovery library<\/strong>
(2007) Letters in Drug Design and Discovery, 4 (8), pp. 605-610.
DOI: 10.2174\/157018007782794581<\/a><\/p>\n\n\n\n

Collina, S., Rossi, D., Urbano, M., Carnevale Baraglia, A., Azzolina, O.
Microwave and polymer assisted synthesis of a small library of \u03b1,\u03b2-unsaturated methyl esters via the Wittig reaction<\/strong>
(2007) Letters in Organic Chemistry, 4 (6), pp. 384-387.
DOI: 10.2174\/157017807781467650<\/a><\/p>\n\n\n\n

Caballero, J., Fern\u00e1ndez, L., Garriga, M., Abreu, J.I., Collina, S., Fern\u00e1ndez, M.
Proteometric study of ghrelin receptor function variations upon mutations using amino acid sequence autocorrelation vectors and genetic algorithm-based least square support vector machines<\/strong>
(2007) Journal of Molecular Graphics and Modelling, 26 (1), pp. 166-178.
DOI: 10.1016\/j.jmgm.2006.11.002<\/a><\/p>\n\n\n\n

Collina, S., Loddo, G., Urbano, M., Linati, L., Callegari, A., Ortuso, F., Alcaro, S., Laggner, C., Langer, T., Prezzavento, O., Ronsisvalle, G., Azzolina, O.
Design, synthesis, and SAR analysis of novel selective \u03c31 ligands<\/strong>
(2007) Bioorganic and Medicinal Chemistry, 15 (2), pp. 771-783.
DOI: 10.1016\/j.bmc.2006.10.048<\/a><\/p>\n\n\n\n

Caballero, J., Zampini, F.M., Collina, S., Fern\u00e1ndez, M.
Quantitative structure-activity relationship modeling of growth hormone secretagogues agonist activity of some tetrahydroisoquinoline 1-carboxamides<\/strong>
(2007) Chemical Biology and Drug Design, 69 (1), pp. 48-55.
DOI: 10.1111\/j.1747-0285.2007.00467.x<\/a><\/p>\n\n\n\n

Brusotti, G., Habermann, J., Azzolina, O., Collina, S.
Preparation of arene carboxylic acids via a polymer-supported Kr\u00f6hnke reaction<\/strong>
(2006) Letters in Organic Chemistry, 3 (12), pp. 943-947.
DOI: 10.2174\/157017806779468077<\/a><\/p>\n\n\n\n

Azzolina, O., Collina, S., Urbano, M., Fata, E., Loddo, G., Linati, L., Lanza, E., Barbieri, A.
Highly diastereoselective synthesis of enantiopure naphthylaminoalcohols with analgesic properties<\/strong>
(2006) Chirality, 18 (10), pp. 841-848.
DOI: 10.1002\/chir.20328<\/a><\/p>\n\n\n\n

Martino, E., Ramaiola, I., Urbano, M., Bracco, F., Collina, S.
Microwave-assisted extraction of coumarin and related compounds from Melilotus officinalis<\/em> (L.) Pallas as an alternative to Soxhlet and ultrasound-assisted extraction<\/strong>
(2006) Journal of Chromatography A, 1125 (2), pp. 147-151.
DOI: 10.1016\/j.chroma.2006.05.032<\/a><\/p>\n\n\n\n

Azzolina, O., Collina, S., Rossi, D., Carnevale Baraglia, A., Alcaro, S., Artese, A.
High-throughput lipophilicity screening of opioid-like analgesics: Validation of computational methods by means of RP-HPLC analysis<\/strong>
(2006) Letters in Drug Design and Discovery, 3 (6), pp. 413-418.
DOI: 10.2174\/157018006777805530<\/a><\/p>\n\n\n\n

Collina, S., Loddo, G., Urbano, M., Rossi, D., Mamolo, M.G., Zampieri, D., Alcaro, S., Gallelli, A., Azzolina, O.
Enantioselective chromatography and absolute configuration of N,N-dimethyl-3-(naphthalen-2-yl)-butan-1-amines: Potential Sigma1 ligands<\/strong>
(2006) Chirality, 18 (4), pp. 245-253.
DOI: 10.1002\/chir.20227<\/a><\/p>\n\n\n\n

Collina, S., Urbano, M., Magnani, A., Loddo, G., Azzolina, O.
Efficient microwave and phosphane-free synthesis of trisubstituted olefins via heck coupling<\/strong>
(2006) Letters in Organic Chemistry, 3 (1), pp. 16-20.
DOI: 10.2174\/157017806774964549<\/a><\/p>\n\n\n\n

Collina, S., Rossi, D., Loddo, G., Barbieri, A., Lanza, E., Linati, L., Alcaro, S., Gallelli, A., Azzolina, O.
Chiral arylpyrrolidinols: Preparation and biological profile<\/strong>
(2005) Bioorganic and Medicinal Chemistry, 13 (9), pp. 3117-3126.
DOI: 10.1016\/j.bmc.2005.02.054<\/a><\/p>\n\n\n\n

Collina, S., Loddo, G., Barbieri, A., Linati, L., Alcaro, S., Chimenti, P., Azzolina, O.
Microwave assisted synthesis of chiral pyrrolines with biological activity<\/strong>
(2004) Tetrahedron Asymmetry, 15 (22), pp. 3601-3608.
DOI: 10.1016\/j.tetasy.2004.10.001<\/a><\/p>\n\n\n\n

Azzolina, O., Collina, S., Brusotti, G., Loddo, G., Linati, L., Lanza, E., Ghislandi, V.
Diastereoselective synthesis of chiral nonracemic naphthylaminoalcohols with analgesic activity<\/strong>
(2004) Tetrahedron Asymmetry, 15 (10), pp. 1651-1658.
DOI: 10.1016\/j.tetasy.2004.03.036<\/a><\/p>\n\n\n\n

Azzolina, O., Collina, S., Brusotti, G., Rossi, D., Linati, L., Lanza, E., Ghislandi, V.
Preparation of novel analgesics via diastereoselective nucleophilic addition to 1-dimethylamino-2-methylpentan-3-one<\/strong>
(2004) Tetrahedron Letters, 45 (7), pp. 1355-1357.
DOI: 10.1016\/j.tetlet.2003.12.060<\/a><\/p>\n\n\n\n

Collina, S., Azzolina, O., Vercesi, D., Brusotti, G., Rossi, D., Barbieri, A., Lanza, E., Mennuni, L., Alcaro, S., Battaglia, D., Linati, L., Ghislandi, V.
Synthesis and pharmacological evaluation of new N-methyl-arylpyrrolidinols with analgesic activity<\/strong>
(2003) Farmaco, 58 (9), pp. 939-946.
DOI: 10.1016\/S0014-827X(03)00152-6<\/a><\/p>\n\n\n\n

Anzini, M., Canullo, L., Braile, C., Cappelli, A., Gallelli, A., Vomero, S., Menziani, M.C., De Benedetti, P.G., Rizzo, M., Collina, S., Azzolina, O., Sbacchi, M., Ghelardini, C., Galeotti, N.
Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as \u03ba-opioid receptor agonists endowed with antinociceptive and antiamnesic activity<\/strong>
(2003) Journal of Medicinal Chemistry, 46 (18), pp. 3853-3864.
DOI: 10.1021\/jm0307640<\/a><\/p>\n\n\n\n

Azzolina, O., Collina, S., Brusotti, G., Rossi, D., Callegari, A., Linati, L., Barbieri, A., Ghislandi, V.
Chemical and biological profile of racemic and optically active dialkylaminoalkylnaphthalenes with analgesic activity<\/strong>
(2002) Tetrahedron Asymmetry, 13 (10), pp. 1073-1081.
DOI: 10.1016\/S0957-4166(02)00241-0<\/a><\/p>\n\n\n\n

Cappelli, A., Anzini, M., Vomero, S., Mennuni, L., Makovec, F., Doucet, E., Hamon, M., Menziani, M.Cristina, De Benedetti, P.G., Giorgi, G., Ghelardini, C., Collina, S.
Novel potent 5-HT3 receptor ligands based on the pyrrolidone structure: Synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities<\/strong>
(2002) Bioorganic and Medicinal Chemistry, 10 (3), pp. 779-801.
DOI: 10.1016\/S0968-089<\/a>6(01)00332-7<\/p>\n\n\n\n

Azzolina, O., Collina, S., Linati, L., Anzini, M., Cappelli, A., Scheideler, M.A., Sbacchi, M.
Enantiomers of 2-[(acylamino)ethyl]-1,4-benzodiazepines, potent ligands of \u03ba-opioid receptor: Chiral chromatographic resolution, configurational assignment, and biological activity<\/strong>
(2001) Chirality, 13 (9), pp. 606-612.
DOI: 10.1002\/chir.1185<\/a><\/p>\n\n\n\n

Collina, S., Azzolina, O., Vercesi, D., Barbieri, A., Lanza, E., Linati, L., Ghislandi, V.
Synthesis of pyrrolinylnaphthalenes and evaluation of their antinociceptive activity<\/strong>
(2000) Farmaco, 55 (9-10), pp. 611-618.
DOI: 10.1016\/s0014-827x(00)00078-1<\/a><\/p>\n\n\n\n

Collina, S., Azzolina, O., Vercesi, D., Sbacchi, M., Scheideler, M.A., Barbieri, A., Lanza, E., Ghislandi, V.
Synthesis and antinociceptive activity of pyrrolidinylnaphthalenes<\/strong>
(2000) Bioorganic and Medicinal Chemistry, 8 (8), pp. 1925-1930.
DOI: 10.1016\/S0968-0896(00)00117-6<\/a><\/p>\n\n\n\n

Collina, S., Azzolina, O., Vercesi, D., Benevelli, F., Callegari, A., Tadini, C., Lanza, E., Barbieri, A., Ghislandi, V.
Dialkylaminoalkylnaphthalenes as novel opioid-like analgesics<\/strong>
(2000) Bioorganic and Medicinal Chemistry, 8 (4), pp. 769-775.
DOI: 10.1016\/s0968-0896(00)00011-0<\/a><\/p>\n\n\n\n

Collina, S., Benevelli, F., Vercesi, D., Ghislandi, V.
On the enantiomers of 2-dimethylamino-3-pentanone, key intermediates in the synthesis of analgesic alkylaminoalkylnaphthalenes<\/strong>
(1999) Tetrahedron Asymmetry, 10 (12), pp. 2387-2397.
DOI: 10.1016\/S0957-4166(99)00223-2<\/a><\/p>\n\n\n\n

Ghislandi, V., Collina, S., Azzolina, O., Barbieri, A., Lanza, E., Tadini, C.
Preparation and configuration of racemic and optically active analgesic cycloaminoalkylnaphthalenes<\/strong>
(1999) Chirality, 11 (1), pp. 21-28.
DOI: 110.1002\/(SICI)1520-636X(1999)11:1<21::AID-CHIR4>3.0.CO;2-4<\/a><\/p>\n\n\n\n

Azzolina, O., Dal Piaz, V., Collina, S., Giovannoni, M.P., Tadini, C.
Chiral resolution and absolute configuration of the enantiomers of 5- acetyl-2-methyl-4-methylsulfinyl-6-phenyl-3(2H)-pyridazinone and evaluation of their platelet aggregation inhibitory activity<\/strong>
(1997) Chirality, 9 (7), pp. 681-685.
DOI: 10.1002\/(SICI)1520-636X(1997)9:7<681::AID-CHIR8>3.0.CO;2-A<\/a><\/p>\n\n\n\n

Azzolina, O., Collina, S., Vercesi, D., Ghislandi, V., Bonabello, A., Galmozzi, M.R.
Chiral resolution, configurational study and pharmacological profile of 2-phenoxypropionic acids<\/strong>
(1997) Farmaco, 52 (6-7), pp. 449-456.
https:\/\/www.scopus.com\/inward\/record.uri?eid=2-s2.0-0030690023&partnerID=40&md5=a18ffb7173f19a6cb9d03b77a8abaa88<\/p>\n\n\n\n

Azzolina, O., Collina, S., Vercesi, D.
Stereoselective hydrolysis by esterase: A strategy for resolving 2-(R,R’-phenoxy)propionyl ester racemates<\/strong>
(1995) Farmaco, 50 (10), pp. 725-733.
https:\/\/www.scopus.com\/inward\/record.uri?eid=2-s2.0-0029616466&partnerID=40&md5=06c4d9af18107f02951ace4edb152536<\/p>\n\n\n\n

Azzolina, O., Collina, S.
Chiral recognition of alkyl 2-aryloxypropionates by HPLC<\/strong>
(1995) Journal of Liquid Chromatography, 18 (1), pp. 81-92.
DOI: 10.1080\/10826079508009222<\/a><\/p>\n\n\n\n

Azzolina, O., Vercesi, D., Collina, S., Ghislandi, V.
Chiral resolution of methyl 2-aryloxypropionates by biocatalytic stereospecific hydrolysis<\/strong>
(1995) Farmaco, 50 (4), pp. 221-226.
https:\/\/www.scopus.com\/inward\/record.uri?eid=2-s2.0-0029048698&partnerID=40&md5=c4bb334a748d60ed9f8013235d46d355<\/p>\n\n\n\n

Collina, S., Gamba, A., Ghislandi, V., Azzolina, O.
Preparation of (+)\u2010 and (\u2212)\u20101,2\u2010dimethyl\u20103\u2010pyrrolidone and stability studies<\/strong>
(1995) Chirality, 7 (6), pp. 439-445.
DOI: 10.1002\/chir.530070609<\/a><\/p>\n\n\n\n

Ghislandi, V., Azzolina, O., Collina, S., Paroli, E., Antonilli, L., Giuseppetti, G., Tadini, C.
Preparation and configuration of racemic and optically active analgesic dialkylaminoalkylnaphthalenes<\/strong>
(1994) Chirality, 6 (5), pp. 389-399.
DOI: 10.1002\/chir.530060506<\/a><\/p>\n\n\n\n

Azzolina, O., Collina, S., Ghislandi, V.
Optical resolution of aryloxypropionic acids and their esters by HPLC on cellulose tris-3,5-dimethyl-triphenylcarbamate derivative<\/strong>
(1993) Farmaco, 48 (10), pp. 1401-1416.
https:\/\/www.scopus.com\/inward\/record.uri?eid=2-s2.0-0027145157&partnerID=40&md5=1832a5f01e5fe09a434141ac3c1052df<\/p>\n\n\n\n

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Cavalloro, V.;\u00a0Malacrida, A.; Miloso, M.;\u00a0Ronchi, D.;\u00a0Porta, A.; Fossati, A.;\u00a0Gheza, G.;\u00a0De Siervi, S.;\u00a0Mantovani, S.;\u00a0Oliviero, B.;\u00a0Mondelli, M.U.;\u00a0Pugliese, L.;\u00a0Turato, C.;\u00a0Martino, E.;\u00a0Collina, S.From lichen to organoids: Usnic acid enantiomers<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/labmedchem.unipv.it\/index.php\/wp-json\/wp\/v2\/pages\/398"}],"collection":[{"href":"https:\/\/labmedchem.unipv.it\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labmedchem.unipv.it\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labmedchem.unipv.it\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labmedchem.unipv.it\/index.php\/wp-json\/wp\/v2\/comments?post=398"}],"version-history":[{"count":37,"href":"https:\/\/labmedchem.unipv.it\/index.php\/wp-json\/wp\/v2\/pages\/398\/revisions"}],"predecessor-version":[{"id":1006,"href":"https:\/\/labmedchem.unipv.it\/index.php\/wp-json\/wp\/v2\/pages\/398\/revisions\/1006"}],"wp:attachment":[{"href":"https:\/\/labmedchem.unipv.it\/index.php\/wp-json\/wp\/v2\/media?parent=398"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}