Sigma-1 Receptor

Sigma-1 receptor agonists acting on aquaporin-mediated h2o2 permeability: New tools for counteracting oxidative stress

10 Settembre 2021 admin Bioactive Compound Synthesis and Design, Publication

Pellavio, G., Rossino, G., Gastaldi, G., Rossi, D., Linciano, P., Collina, S., Laforenza, U. International Journal of Molecular Sciences, 22 (18), 2021. DOI: 10.3390/ijms22189790 ABSTRACT.

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Gellan-based composite system as a potential tool for the treatment of nervous tissue injuries: Cross-linked electrospun nanofibers embedded in a RC-33-loaded freeze-dried matrix

26 Gennaio 2021 admin Bioactive Compound Synthesis and Design, Publication

Vigani, B., Valentino, C., Cavalloro, V., Catenacci, L., Sorrenti, M., Sandri, G., Bonferoni, M.C., Bozzi, C., Collina, S., Rossi, S., Ferrari, F. Pharmaceutics, 13 (2),

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Setup and validation of a reliable docking protocol for the development of neuroprotective agents by targeting the Sigma-1 receptor (S1R)

16 Novembre 2020 admin Bioactive Compound Synthesis and Design, Publication

Rossino, G., Rui, M., Pozzetti, L., Schepmann, D., Wünsch, B., Zambieri, D, Pellavio, G., Laforenza, U., Rinaldi, S., Colombo, G., Morelli, L., Linciano, P., Rossi, D., Collina,

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Pan-sigma receptor modulator rc-106 induces terminal unfolded protein response in in vitro pancreatic cancer model

13 Ottobre 2020 admin Bioactive Compound Synthesis and Design, Publication

Cortesi, M., Zamagni, A., Pignatta, S., Zanoni, M., Arienti, C., Rossi, D., Collina, S., Tesei, A. International Journal of Molecular Sciences, 21 (23), 2020. DOI:

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Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents

30 Giugno 2020 admin Bioactive Compound Synthesis and Design, Publication

Listro, R., Stotani, S., Rossino, G., Rui, M., Malacrida, A., Cavaletti, G., Cortesi, M., Arienti, C., Tesei, A., Rossi, D., Giacomo, M.D., Miloso, M., Collina,

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Dual-functioning scaffolds for the treatment of spinal cord injury: Alginate nanofibers loaded with the sigma 1 receptor (S1R) Agonist RC-33 in chitosan films

26 Dicembre 2019 admin Publication

Vigani, B., Rossi, S., Sandri, G., Bonferoni, M.C., Rui, M., Collina, S., Fagiani, F., Lanni, C., Ferrari, F. Mar. Drugs 2020, 18(1), 21; https://doi.org/10.3390/md18010021 ABSTRACT.

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New Insights into the Opening of the Occluded Ligand-Binding Pocket of Sigma1 Receptor: Binding of a Novel Bivalent RC-33 Derivative

6 Dicembre 2019 admin Bioactive Compound Synthesis and Design, Publication

Rossino, G., Orellana, I., Caballero, J., Schepmann, D., Wünsch, B., Rui, M., Rossi, D., González-Avendaño, M., Collina, S., Vergara-Jaque, A. J. Chem. Inf. Model. 2020,

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